THE SENSORY ORGANS

 

THE SENSORY ORGANS

PREPARED BY MR. ABHIJIT DAS

 

THE EYE

Eyes are located in sockets of the skull called orbits. The human eyeball is a spherical structure.

The eyeball wall is composed of three layers.

 Figure Credit: Sonalika Pradhan


The external layer is composed of dense connective tissue and is called sclera. The anterior portion of sclera is called cornea.

The middle layer contains many blood vessels and is called choroid. The choroid is bluish in colour. The choroid layer becomes thick in the anterior part to form the ciliary body. The ciliary body itself continues forward to form the iris which is the visible coloured portion of the eye.

Eyes contain a transparent lens which is held by ligaments attached to the ciliary body.

The hole located in the centre of the iris of the eye that allows light to strike the retina is called pupil.

The inner layer is the retina. Retina contains three layers of neural cells; photoreceptor layer, bipolar layer and multipolar layer.

Photoreceptor layer consists of photoreceptor cells. There are two types of photoreceptor cells; rods and cones. These cells contain light sensitive proteins called the photopigments.

The rods are responsible for twilight (scotopic) vision and the cones are responsible for daylight (photopic) vision and colour vision.

The rods contain a photopigment called the rhodopsin.

There are three types of cones which have their own pigments that respond to red, green and blue lights.

The pigments respond to red light is erythropsin, the pigments respond to blue light is cyanopsin and the pigments respond to green light is chloropsin.

The sensation of different colours are produced by various combinations of these cones and their pigments.

There is a region in the eyeball where the optic nerves leave the eye and the retinal blood vessels enter the eye. Photoreceptor cells are absent in that region and hence it is called the blind spot.

There is another region at the posterior pole of the eye called macula lutea with a central pit called fovea. The fovea is the location where only cones are densely packed and is called yellow spot. It is the point where the visual resolution is the greatest.

The space between the cornea and the lens is the aqueous chamber which contains a watery fluid called aqueous humor.

The space between the lens and the retina is called the vitreous chamber which contains a transparent gel called vitreous humor.

MECHANISM OF VISION

The light rays are focused on the retina through the lens. These light rays generate action potential in the rods and cones.

The photopigments in the human eyes are composed of opsin (a protein) and retinal (an aldehyde of vitamin A).

When light falls on photopigments , the retinal gets separated from opsin and this process is known as bleaching of pigments. This is how potential differences (action potentials) are generated in the photoreceptor cells.

This produces a signal that generates action potentials in the bipolar cells.

Then ultimately, the multipolar cells get depolarized.

Now these action potentials are transmitted by the optic nerves to the visual sensory area of the cerebrum, where the impulses are analysed and the image formed on the retina is recognized based on earlier memory.

THE EAR


 Figure Credit: Sonalika Pradhan

The human ear can be divided into three major sections; the outer ear, the middle ear, and the inner ear.

The outer ear consists of the pinna and external auditory meatus (canal) and tympanic membrane.

The pinna collects the vibration from the air which produce sound. The external auditory meatus extends up to the tympanic membrane (or the ear drum). There are very fine hair and ceruminous glands which produce ear wax.

The tympanic membrane is composed of connective tissues.

The middle ear contains three ossicles (bones) called malleus, incus and stapes which are attached to one another.

The malleus is attached to the tympanic membrane and the stapes is attached to the oval window of the cochlea.

The ossicles present inside the inner ear increase the efficiency of transmission of sound waves to the inner ear.

A tube called eustachian tube connects the middle ear cavity with the pharynx. The tube helps in equalising the pressure on either side of the tympanic membrane.

The inner ear is called labyrinth which has two parts; the bony labyrinth and the membranous labyrinth.

MECHANISM OF HEARING

The bony labyrinth of the inner ear is a series of channels. Inside this bony labyrinth lies the membranous labyrinth, which is surrounded by a fluid called perilymph and the membranous labyrinth is filled with a fluid called endolymph.

The coiled part of the inner ear is called cochlea. Inside cochlea the upper membrane of the membranous labyrinth is called the reissner’s membrane and the lower membrane of the membranous labyrinth is called the basilar membrane.



A structure called the organ of corti is located on the basilar membrane which contain hair cells that acts as auditory receptors. The basal end of the hair cells are in close contact with nerve fibres.

Some projections called stereo cilia are projected from the tip of each hair cells.

Another thin elastic membrane is present above the hair cells called the tectorial membrane.



The external ear receives sound waves and transfers the sound waves to the tympanic membrane.

The tympanic membrane vibrates in response to the sound waves and these vibrations are transmitted through the ear bones (malleus, incus and stapes) to the inner ear.

The vibrations are then passed to the fluid of the cochlea, where they generate waves in the fluids.

The waves in the fluids induce a movement in the basilar membrane. These movements of the basilar membrane bend the hair cells, pressing their stereo cilia against the tectorial membrane.

As a result action potentials are generated in the associated neurons present below the hair cells.

These action potentials are transmitted via auditory nerves to the auditory sensory area of the cerebrum, where the impulses are analysed and the sound is recognized.

MECHANISM OF BALANCE

The inner ear also contains another structure called vestibular apparatus composed of three semicircular canals (bony) and the otolith organs (saccule and utricle).

Each semicircular canal lies in a different plane at right angles to each other.

There are membranous canals which are suspended in the perilymph of the semicircular canals.

The base of semicircular canal is swollen and is called ampulla, which contains a raised structure called crista ampullaris. Crista ampullaris has hair cells. These hair cells are specific receptors of the vestibular apparatus responsible for dynamic equilibrium of the body.



The otolith organs also have raised structures called macula. Macula has hair cells. These hair cells act as receptors responsible for the static equilibrium of the body.



So the semicircular canal and the otolith organs are concerned with equilibrium of the body.

The arrangement of semicircular canals and otolith organs allows perception not only of the position of the head in space but also the direction and rate of any movement.

Any change of position of the head causes movement in the endolymph containing the hair cells, which moves them and generates action potentials in the sensory nerves present in the otolith organs and the semicircular canals.

These action potentials are transmitted by the vestibular nerve, which joins the cochlear nerve to form the vestibulocochlear nerve.

The vestibular branch then passes to the cerebellum. Thereafter, impulses are transmitted to the cerebrum and the skeletal muscles, enabling perceptions of any adjustments needed to maintain balance or equilibrium.

SENSE OF SMELL

The sense of smell or olfaction originates in the nasal cavity.

MECHANISM OF SMELL

All odorous materials have volatile molecules, which are carried into the nose by air.

When these molecules are dissolved in mucus, they stimulate the olfactory nerves present in the mucus membrane of the roof of the nasal cavity.

On each side of the nasal septum olfactory nerve fibres pass to the olfactory bulb, where synapses occur.

From the olfactory bulb, bundles of nerve fibres passes to the olfactory sensory area in the temporal lobe of the cerebrum, where the impulses are interpreted and odour perceived.


THE SKIN

Skin is the largest sensory organ, and it plays a crucial role in perception of the external environment. It is equipped with a variety of sensory receptors that allow to respond to different stimuli. These sensory receptors are responsible for various types of sensations, including touch, pressure, temperature, pain, and even a sense of one's body position in space (proprioception).

The skin consists of three primary layers:

1.     Epidermis: The epidermis is the outermost layer of the skin, serving as a protective barrier between the body and the external environment. It is avascular (lacks blood vessels) and primarily composed of stratified squamous epithelial cells. Melanocytes within the epidermis produce melanin, the pigment responsible for skin color.

2.     Dermis: The dermis is the layer beneath the epidermis and is primarily composed of connective tissue. It provides structural strength and elasticity to the skin. The dermis contains a network of collagen and elastin fibers, which give the skin its flexibility and resilience. This layer contains various supporting structures, such as hair follicles, sweat glands, sebaceous (oil) glands, blood vessels.

3.     Subcutaneous Tissue (Hypodermis): The subcutaneous tissue, also known as the hypodermis or superficial fascia, is located beneath the dermis. It consists mainly of fat cells (adipocytes) and connective tissue. The hypodermis provides insulation and padding, helping to regulate body temperature and protect underlying structures.

INJECTIONS ADMINISTERED INTO THE SKIN

1.     Intradermal Injections: These injections are administered into the dermis of the skin. Intradermal injections are typically given at an angle (5-15 degrees) and are often used for allergy testing and some vaccines, such as the tuberculosis (TB) skin test.

2.     Subcutaneous Injections: Subcutaneous injections are delivered just beneath the skin into the subcutaneous tissue. The needle is typically inserted at a 45-degree angle to the skin. Subcutaneous injections are commonly used for medications that need to be absorbed slowly, like insulin or some vaccines.

3.     Intramuscular Injections: Intramuscular injections are administered into the muscle tissue beneath the skin. In adults, a 90-degree angle (perpendicular to the skin) is typically used. Intramuscular injections are often used for a wide range of medications, including vaccines, antibiotics, and certain hormones.


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